Alter Your DNA, Be Safe From Life-threatening Diseases

Alter Your DNA, Be Safe From Life-threatening Diseases
IAEA fellows from different countries in training under the guidance of the IAEA Plant Breeding Unit at Seibersdorf, Austria. IAEA Imagebank / Flickr CC BY-SA 2.0

Genetic mutation is often correlated to serious disorders, but a new study yielded a result that might challenge this belief.


In fact, their study proved, so far, that mutation in the genes could provide a protective mechanism to the person. The study, which was published in Nature Biotechnology, has looked into the dynamics of some 600,000 individuals’ genes and their likelihood of developing certain types of diseases.

While the study has provided yet another plausible link between genes and the development of certain illnesses, which has been well documented in previous literature, it has provided a newer perspective on the role of genetic mutation on the person’s health.

The study particularly found a fascinating body of evidence to support that error in genetic make up, which is a natural occurrence in the natural world, could actually provide a protective mechanism against a certain diseases.

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In order to establish this link, the research team, composed of geneticists and other allied health researchers, has deviated from the traditional way of studying the role of genetics and its relationship to human health. Instead, the cross-cultural researchers examined individuals who showed genetic precursors to certain diseases but did not actually develop those diseases as adults.

From DNA samples from 589,306 individuals, the researchers have identified 13 individuals who should have developed one of eight genetic diseases but did not. But the study is far from perfect; it could be possible that those who showed “resilience” to certain diseases could have been affected by factors other than the protective mechanism as a direct result of the gene mutation.

“The identification of resilient individuals may provide a first step toward uncovering protective genetic variants that could help elucidate the mechanisms of Mendelian diseases and new therapeutic strategies,” an excerpt of the study reads.

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